This evidence-based stroke nursing care plan combines NANDA-I diagnoses, Cochrane evidence, and AHA/ASA/NICE guidelines for optimal patient outcomes. Key components include NIH Stroke Scale monitoring, dysphagia screening (TOR-BSST), thrombolytic therapy (tPA within 4.5 hours), and early mobility protocols. Goals focus on SMART targets like aspiration prevention, Barthel Index improvement, and 30% reduction in hospital-acquired injuries. Aligns with Joint Commission standards and interprofessional collaboration (SLP, PT, pharmacists) for scalable stroke care in acute and rehab settings.